Syed Musthapa Meeran Selected Research

Centchroman

1/2021	Dietary bioactive diindolylmethane enhances the therapeutic efficacy of centchroman in breast cancer cells by regulating ABCB1/P-gp efflux transporter.
9/2020	Centchroman prevents metastatic colonization of breast cancer cells and disrupts angiogenesis via inhibition of RAC1/PAK1/β-catenin signaling axis.
11/2016	Centchroman altered the expressions of tumor-related genes through active chromatin modifications in mammary cancer.
1/2015	Centchroman suppresses breast cancer metastasis by reversing epithelial-mesenchymal transition via downregulation of HER2/ERK1/2/MMP-9 signaling.

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Syed Musthapa Meeran Research Topics

Disease

15	Neoplasms (Cancer) 09/2022 - 01/2008
11	Breast Neoplasms (Breast Cancer) 12/2021 - 12/2013
7	Neoplasm Metastasis (Metastasis) 12/2021 - 01/2015
4	Lung Neoplasms (Lung Cancer) 09/2022 - 06/2015
4	Carcinogenesis 01/2022 - 12/2013
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2022 - 02/2016
2	Obesity 12/2021 - 12/2013
1	Genomic Instability 09/2022
1	COVID-19 01/2022
1	Skin Neoplasms (Skin Cancer) 01/2018
1	Melanoma (Melanoma, Malignant) 01/2018
1	Pain (Aches) 05/2016
1	Triple Negative Breast Neoplasms 05/2016
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2008
1	Body Weight (Weight, Body) 01/2008

Drug/Important Bio-Agent (IBA)

7	Pharmaceutical PreparationsIBA 01/2022 - 01/2015
4	CentchromanIBA 01/2021 - 01/2015
4	PhytochemicalsIBA 01/2019 - 01/2015
3	Matrix Metalloproteinases (MMPs)IBA 09/2022 - 01/2015
3	MicroRNAs (MicroRNA)IBA 01/2022 - 12/2020
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2019
3	Oral ContraceptivesIBA 09/2020 - 01/2015
3	cucurbitacin BIBA 02/2016 - 06/2015
2	Histones (Histone)IBA 01/2022 - 11/2016
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2008
2	LeptinIBA 12/2021 - 12/2013
2	CarcinogensIBA 12/2021 - 11/2016
2	EnzymesIBA 12/2020 - 01/2015
2	Messenger RNA (mRNA)IBA 12/2020 - 01/2008
2	Small Interfering RNA (siRNA)IBA 09/2020 - 02/2016
2	CateninsIBA 09/2020 - 02/2016
2	MethyltransferasesIBA 06/2016 - 06/2015
2	DNA (Deoxyribonucleic Acid)IBA 06/2016 - 06/2015
2	Histone Deacetylases (Histone Deacetylase)IBA 06/2016 - 06/2015
2	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 02/2016 - 06/2015
2	TriterpenesIBA 02/2016 - 01/2016
1	AntioxidantsIBA 09/2022
1	Cytochromes c (Cytochrome c)IBA 09/2022
1	Caspase 3 (Caspase-3)IBA 09/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Untranslated RNA (Noncoding RNA)IBA 01/2022
1	Immunologic Factors (Immunomodulators)IBA 01/2022
1	piperineIBA 12/2021
1	Antineoplastic Agents (Antineoplastics)IBA 12/2021
1	AlkaloidsIBA 12/2021
1	APTIBA 10/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2021
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021
1	Selective Estrogen Receptor Modulators (SERM)IBA 01/2021
1	3,3'-diindolylmethane (diindolylmethane)IBA 01/2021
1	multidrug resistance-associated protein 1IBA 01/2021
1	fluorexon (calcein)IBA 01/2021
1	Long Noncoding RNAIBA 12/2020
1	Monomeric GTP-Binding ProteinsIBA 09/2020
1	CurcuminIBA 01/2019
1	TeaIBA 01/2019
1	ResveratrolIBA 01/2019
1	PolyphenolsIBA 01/2019
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2019
1	sulforaphaneIBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	GenisteinIBA 01/2019
1	ChromatinIBA 11/2016
1	IodineIBA 05/2016
1	Metalloproteases (Metalloproteinases)IBA 05/2016
1	Zoledronic Acid (Zometa)FDA Link 05/2016
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016
1	Histone Deacetylase InhibitorsIBA 06/2015
1	RNA (Ribonucleic Acid)IBA 01/2015
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2015
1	OligonucleotidesIBA 01/2015
1	Estrogens (Estrogen)FDA Link 12/2013
1	AdiponectinIBA 12/2013
1	Interleukin-6 (Interleukin 6)IBA 12/2013
1	AdipokinesIBA 12/2013
1	CytokinesIBA 12/2013
1	Cyclin D1IBA 01/2008
1	NF-kappa B (NF-kB)IBA 01/2008
1	Grape Seed ProanthocyanidinsIBA 01/2008
1	Proanthocyanidins (Procyanidins)IBA 01/2008
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2008

Therapy/Procedure

11	Therapeutics 01/2022 - 02/2016
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2019
1	Immunotherapy 01/2022
1	Oral Administration 12/2021
1	Caloric Restriction 06/2016
1	Neoadjuvant Therapy 05/2016
1	Chemoprevention 01/2008